Joints

Osteoarthritis

Osteoarthritis is the progressive loss of the cartilage that lines a joint, together with changes in the underlying bone, the joint lining and the surrounding soft tissues. It is a disease of the whole joint rather than simple mechanical wear, and it most commonly affects the knees, hips, hands and spine. Symptoms and the appearance on X-ray correlate poorly: substantial radiographic change can cause little trouble, and significant pain can occur with modest findings.

A clinician examining the leg of a seated patient

Symptoms

The pattern differs from inflammatory arthritis in ways that are usually apparent from the history alone.

Causes and risk factors

Several factors combine, and some of them are modifiable — which is where treatment has the most leverage.

Common questions

Will exercise damage the joint further?

Appropriate exercise does not accelerate osteoarthritis and is one of the better-supported treatments for it. Activity is typically adjusted in type and volume rather than avoided.

My X-ray looks bad — does that predict how I will do?

Poorly, in either direction. Radiographic severity and symptoms correlate weakly, which is why treatment decisions are based primarily on pain and function.

Do supplements help?

Evidence for glucosamine and chondroitin is mixed and generally weak. They are not recommended in most current guidelines, though they are widely used and generally regarded as low-risk.

Is it the same as rheumatoid arthritis?

No. Rheumatoid arthritis is a systemic autoimmune disease with a different pattern, prolonged morning stiffness and different treatment. The distinction is made clinically and with blood tests where needed.

General reference information, and not advice about your own case. It may not reflect the most recent guidance or what is offered on a given day — call (201) 408-5151 to check.

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